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http://hdl.handle.net/20.500.11960/3820
Título: | The efficacy of neutraceuticals to alleviate dog osteoarthritis symptoms, a meta-analysis of case-control trials |
Autores: | Mata, Fernando Dormer, Luisa |
Palavras-chave: | Case-control trials Dog osteoarthritis Meta-analysis Nutraceuticals Pain relief |
Data: | 1-Ago-2023 |
Citação: | Mata, F., & Dormer, L. (2023). The efficacy of neutraceuticals to alleviate dog osteoarthritis symptoms, a meta-analysis of case-control trials. Veterinarski Arhiv, 93(3), 351-360. https://doi.org/10.24099/vet.arhiv.1737 |
Resumo: | Osteoarthritis is a common condition in dogs. Non-steroidal anti-inflammatory drugs are currently the most widely used treatment option; however, their chronic use is associated with numerous malefic side effects, including death. There has been increased interest in alternative treatments and nutraceuticals have assumed fundamental importance. A number of individual studies and systematic reviews have been done, but no meta-analysis has been produced to date. By conducting a meta-analysis, we aimed to fill this research gap. We combined the results of 13 case placebo controlled trials in a single major study, to determine the efficacy of nutraceuticals in alleviating symptoms of osteoarthritis. A population of 638 dogs was used, from which 327 were treated with nutraceuticals and 321 were used as controls. A successful random effects model was adjusted (P<0.001), with a risk ratio of 0.62 within a 95% CI of [0.47; 0.81], favouring the use of nutraceuticals. The nutraceuticals used in the trials were green-lipped mussel, chondroitin sulphate, an extract of India and Java turmeric (P54FP), a homeopathic combination preparation known as Zeel®, Ω-3 fatty acids, deep sea fish oil, a mix of glucosamine with chondroitin sulphate and hyaluronic acid, and cannabidiol. |
URI: | http://hdl.handle.net/20.500.11960/3820 |
ISSN: | 0372-5480 |
Aparece nas colecções: | CISAS - Artigos indexados à WoS/Scopus |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2023-93-3-8.pdf | 642.45 kB | Adobe PDF | Ver/Abrir |
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